Chitkara Open Access Journals - Blog

Antibiofilm Potential of Metal Based Nanoparticles: Synthesis and Mode of Action

Abstract:

Biofilm refers to a group of microbes colonizing together and often adhered to a surface. The adherence is attributed to secretion of polymeric substances comprising of extracellular DNA, proteins, and polysaccharides thereby limiting the access and inhibitory activity of existing antimicrobial agents. Biofilm are a major cause of acute infections and pose immense clinical threat especially in conditions employing the use of invasive devices thus being a major source of mortality and morbidity. Hence there is a dire need to develop alternative treatment against biofilm-related infections. Advances in nanotechnology has opened new horizons. Nanoparticles derived from various metal present promising candidates to ameliorate biofilms owing to their antioxidant potential.

Author:

  • R Kaur: Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • M Khurana: Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • R K Virk: Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • A Sharma: Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India

Keywords: 

Biofilm, metals, Nanoparticles, Formulation methods

URL:

https://jmrh.chitkara.edu.in/index.php/jmrh/article/view/2

References

Ahire, J., Hattingh, M., Neveling, D. P. and Dicks, L. M. (2016). Copper-Containing Anti-Biofilm Nanofiber Scaffolds as a Wound Dressing Material. PLoS ONE, 11(13). https://doi.org/10.1371/journal.pone.0152755
Ahmed, S., Ahmad, M., Swami, B. L., Ikram, S. (2016). A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: A green expertise. Journal of Advanced Research, 7, 17–28. https://doi.org/10.1016/j.jare.2015.02.007 …….