Epigenetic modification acetylation or deacetylation of histone considered as an important element in various disorders. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are the enzymes which catalyse the acetylation and deacetylation of histone respectively. It helps in regulating the condensation of chromatin and transcription of genes.
Kajal Thapa, Savir Kumar, Anurag Sharma, Sandeep Arora, Amarjot Kaur Grewal and Thakur Gurjeet Singh, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab-140401
Epigenetic, Histone, Acetylation, Deacetylation, Lysine, Histone deacetylases inhibitors
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