Chitkara Open Access Journals - Blog

Treatment of Dental Caries by Ozone Therapy – A Review

Ozone, a powerful oxidizer effectively kills bacteria, fungi, viruses and parasites at a dramatically lower concentration and also has the capacity to stimulate blood circulation, platelets, and immune response. Ozone therapy is a well-established alternative and complementary therapy in most of the European countries. Treatment may be achieved by increasing the resistance of the tooth against the microbial activity and reducing the extent of microbial activity…..


  • Charu KhoslaSchool of Applied sciences, Chitkara University, Punjab, India
  • MamtaResearch scholar of Punjab Technical University, Kapurthala (Asst. Professor, Universal Group of Institutions-Lalru Punjab)
  • AnuradhaResearch scholar of Punjab Technical University, Kapurthala (Asst. Professor, Surya World-Rajpura)


Ozone, Oxygen, Dentistry



Baysan A., Whiley R. A., Lynch E.(2000); Antimicrobial effect of a novel ozone-generating device on micro-organisms associated with primary root carious lesions in vitro. Caries
Res. 34(6), 498–501.

BOCCI V. (1999); Biological and clinical effects of ozone. Has ozone therapy a future in medicine?. Br. J.Biomed. Sci. 56, 270–279.

Estrela C., Estrela C. R. A., Decurcio D. A., Hollanda A. C. B., Silva J. A.(2007); Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in
infected human root canals. Int. Endodont. J. 40, 85–93.

Filippi A. (2006) The influence of ozonised water on the epithelial wound healing process in the oral cavity.Clinic of Oral Surgery, Radiology and Oral Medicine, University of Basel, Switzerland.
Garg R., Tandon S.(2009); Ozone: A new face of dentistry. The Int J Dent Science.; 7, 2.

Greene A. K., Few B. K., Serafini J. C.(1993); A comparison of ozonation and chlorination for the disinfection of stainless steel surfaces. J. Dairy Sci. 76(11), 3617–3620.

Hems R. S., Gulabivala K., Ng Y.-L., Ready D., Spratt D. A.(2005); An in vitro evaluation of
the ability of ozone to kill a strain of Enterococcus faecalis. Int. Endodont. J. 38, 22–29.

Holmes J.(2003); Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18-month trial. Gerodontol. 20(2), 106–114.

Huth K. C., Jacob F .M., Saugel B., Capello C., Paschos E., Hollweck R,. Hickel R., Brand K.(2006); Effect of ozone on oral cells compared woth established antimicrobials. Eur. J.
Oral Sci.114, 435–440.

Kronusova M.(2007); Aplikace atomárního kyslíku v ordinaci praktického zubního lékaře. Progresdent 3, 34–36.

Nagayoshi M., Fukuizumi T., Kitamura C., Yano J., Terashita M., Nishihara T.(2004); Efficacy of ozone on survival and permeability of oral micro-organisms. Oral. Microbiol. Immunol. 19(4), 240–246.

Nanduri.,(2012); Ozone therapy in dentistry, UCLA-International post doctoral training programme