Chitkara Open Access Journals - Blog

UV-Spectrophotometry – Multicomponent Mode of Analysis for Simultaneous Estimation of Brinzolamide and Brimonidine Tartrate in Bulk and Ophthalmic Formulation


Vikram L. Jadhav, Amod S. Patil, Suraj R. Chaudhari and Atul A. Shirkhedkar, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dist.: Dhule (M.S.) India 425 405.


Brinzolamide, Brimonidine tartrate, UV-Spectrophotometry, Multicomponent mode of analysis, Validation


Brinzolamide (BRZ) and Brimonidine Tartrate (BT) in combination are available as an ophthalmic suspension in the ratio of 5:1. A simple, reproducible and efficient method for the simultaneous determination of BRZ and BT in Bulk and Ophthalmic formulation has been developed….