Abstract:

Background: Micro-organisms are responsible for the transmission of a large number of diseases. It is hard to comprehend the amount of diseases, deaths and economic losses caused by micro-organisms alone. Plants are good sources of eco-friendly and readily available antimicrobial agents.
Purpose: The aim of this study was to evaluate the chemical constituents and antimicrobial characteristics of three fractions from ethnomedicinal Icacina trichantha. Oliv. (Icacinaceae).
Methods: Methanol extract from Icacina trichantha. Oliv was obtained by maceration and fractionated successively using hexane, and ethyl acetate. The antimicrobial properties of Icacina trichantha. Oliv was assessed using agar cup diffusion method on MRSA, P. aeruginosa, S. typhi, C. krusei, S. dysenteriae, S. pyrogenes, E. coli, K. pneumoniae, C. albicans, and C. tropicalis. Phytochemical screening on fractions was also evaluated using standard methods….

Author(s):

• Ojah Emmanuel Onah, Medicinal Chemistry Research Group, Organic Chemistry Unit, Department of Chemistry, University of Ibadan, Ibadan-900001, Nigeria
• Kachi Jolly Babangida, Department of Biological Sciences, Federal University Lokoja, P.M.B. 1154, Kogi State, Nigeria

DOI: 

https://doi.org/10.15415/jce.2020.71002

Keywords:

Medicinal plants, Icacina trichantha, Icacinaceae, Phytochemicals, Antimicrobials

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