A GEANT4 Study of a Gamma-ray Collimation Array
Proton beam therapy uses high-energy protons to destroy cancer cells which are still uncertain about where in the body they hit. A possible way to answer this question is to detect the gamma rays produced during the irradiation and determine where in the body they are produced. This work investigates the use of collimators to determine where the proton interactions occur. GEANT4 is used to simulate the gamma production of a source interacting with a collimator. Each event simulates a number of gammas obtained as a function of the position along the detector. Repeating for different collimator configurations can thus help determine the best characteristics of a detector device.
Author(s): J A López, S S Romero González and O Hernández Rodríguez, Physics Department, University of Texas at El Paso, El Paso, Texas, 79968 U.S.A. And J Holmes and R Alarcón, Physics Department, Arizona State University, Tempe, Arizona, 85281 U.S.A.
Keywords: Proton therapy, Collimators, Gamma rays, GEANT4
URL: https://jnp.chitkara.edu.in/index.php/jnp/article/view/225
References:
K. A. Camphausen, R. C. Lawrence, (2009). “Principles of Radiation Therapy”. In R. Pazdur, L. D. Wagman, K. A. Camphausen, W. J. Hoskins, (eds.) Cancer Management: A Multidisciplinary Approach. 11th ed., Cmp. United Business Media. ISBN-13: 978-1891483622.
W. P. Levin, H. Kooy, J. S.Loeffler, T. F., DeLaney, Proton Beam Therapy, British Journal of Cancer 93, 849 (2005). https://doi.org/10.1038/sj.bjc.6602754
James Metz, (2006). “Differences Between Protons and X-rays”. Abramson Cancer Center of the University of Pennsylvania. http://www.oncolink.org/treatment/article.cfm?c=9&s=70&id=210. Accessed 4 February 2018.
W. D. Newhauser and R. Zhang, Phys. Med. Biol. 60, R155 (2015). https://doi.org/10.1088/0031-9155/60/8/R155
Basics physics of nuclear medicine/interaction of radiation with matter. From https://en.wikibooks.org/wiki/Basic_Physics_of_Nuclear_Medicine/Interaction_of_Radiation_with_Matter. Accessed 15/9/2019
M. Chiari, Joint ICTP-IAEA Workshop on Nuclear Data for Analytical Applications. (2013) http://indico.ictp.it/event/a12218/session/23/contribution/14/material/0/0.pdf. Accessed 15 October 2019.
Geant4 official website. http://geant4.cern.ch/support/introductionToGeant4.shtml. Accessed 1 February 2018.
Fiber Optical Networking. http://www.fiber-opticalnetworking.com/getting-know-fiber-collimator.html. Accessed 9 February 2018.
J. T. Bushberg, J. A. Seibert, E. M. Leidholdt, and J. M. Boone, “The Essential Physics of Medical Imaging”, Second ed., Philadelphia: Lippincott Williams & Wilkins, 2006, p. 261. ISBN 9780781780575.
S. S. Romero Gonzalez, (2018). Geant4 study of a gamma ray collimator for proton therapy. M.S. Thesis, University of Texas at El Paso. https://digitalcommons.utep.edu/dissertations/AAI10822888/.Accessed 10 September 2019.